Extranuclear ER&#945; is associated with regression of T47D PKC&#945;-overexpressing, tamoxifen-resistant breast cancer.

Perez White, Bethany; Molloy, Mary Ellen; Zhao, Huiping; Zhang, Yiyun; Tonetti, Debra A

Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer.

Perez White, Bethany; Molloy, Mary Ellen; Zhao, Huiping; Zhang, Yiyun; Tonetti, Debra A.

Affiliation

Perez White B; Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 S, Wood Street, Chicago, IL 60611, USA.

Mol Cancer ; 12: 34, 2013 May 01.

Article in En | MEDLINE | ID: mdl-23634843

Subject(s)

Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Drug Resistance, Neoplasm/genetics; Estrogen Receptor alpha/metabolism; Gene Expression; Protein Kinase C-alpha/genetics; Tamoxifen/pharmacology; Animals; Antineoplastic Agents, Hormonal/administration & dosage; Antineoplastic Agents, Hormonal/pharmacology; Breast Neoplasms/drug therapy; Breast Neoplasms/pathology; Caveolin 1/metabolism; Cell Nucleus/metabolism; Cell Proliferation/drug effects; Cytoplasm/metabolism; Disease Models, Animal; Estradiol/pharmacology; Female; Humans; Mice; Protein Binding; Protein Transport/drug effects; Raloxifene Hydrochloride/administration & dosage; Raloxifene Hydrochloride/pharmacology; Tamoxifen/administration & dosage; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tamoxifen / Breast Neoplasms / Gene Expression / Drug Resistance, Neoplasm / Estrogen Receptor alpha / Protein Kinase C-alpha Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2013 Document type: Article Affiliation country: United States Country of publication: United kingdom

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