Two-photon ratiometric fluorescent mapping of intracellular transport pathways of pH-responsive block copolymer micellar nanocarriers.

Liu, Tao; Hu, Jinming; Jin, Zhenyu; Jin, Fan; Liu, Shiyong

Liu, Tao; Hu, Jinming; Jin, Zhenyu; Jin, Fan; Liu, Shiyong.

Affiliation

Liu T; CAS Key Laboratory of Soft Matter Chemistry, Hefei National Laboratory for Physical Sciences at the Microscale, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, P. R. China.

Adv Healthc Mater ; 2(12): 1576-81, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23703785

Subject(s)

Drug Carriers/chemistry; Fluorescent Dyes/chemistry; Micelles; Nanoparticles/chemistry; Polymers/chemistry; Drug Carriers/pharmacokinetics; Fluorescent Dyes/pharmacokinetics; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liver/chemistry; Liver/metabolism; Microscopy, Confocal; Microscopy, Fluorescence, Multiphoton/methods; Polymers/pharmacokinetics; Spectrometry, Fluorescence

Key words

diblock copolymer micelles; endocytic pathway; intracellular imaging; pH gradients; ratiometric quantification

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Drug Carriers / Nanoparticles / Fluorescent Dyes / Micelles Limits: Humans Language: En Journal: Adv Healthc Mater Year: 2013 Document type: Article Country of publication: Germany

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