PLGA nanoparticle entrapped killed porcine reproductive and respiratory syndrome virus vaccine helps in viral clearance in pigs.

Dwivedi, Varun; Manickam, Cordelia; Binjawadagi, Basavaraj; Renukaradhya, Gourapura J

Dwivedi, Varun; Manickam, Cordelia; Binjawadagi, Basavaraj; Renukaradhya, Gourapura J.

Affiliation

Dwivedi V; Food Animal Health Research Program, Ohio Agricultural Research and Development Center, 1680 Madison Avenue, Wooster, OH 44691, USA.

Vet Microbiol ; 166(1-2): 47-58, 2013 Sep 27.

Article in En | MEDLINE | ID: mdl-23764272

Subject(s)

Porcine Reproductive and Respiratory Syndrome/prevention & control; Porcine respiratory and reproductive syndrome virus/immunology; Viral Vaccines/immunology; Administration, Intranasal; Animals; Antibodies, Viral/blood; CD8-Positive T-Lymphocytes/immunology; Cytokines/genetics; Cytokines/immunology; Lactic Acid/chemistry; Lung/immunology; Lung/virology; Nanoparticles/chemistry; Polyglycolic Acid/chemistry; Polylactic Acid-Polyglycolic Acid Copolymer; Porcine Reproductive and Respiratory Syndrome/genetics; Porcine Reproductive and Respiratory Syndrome/immunology; Porcine Reproductive and Respiratory Syndrome/virology; Porcine respiratory and reproductive syndrome virus/genetics; Porcine respiratory and reproductive syndrome virus/physiology; Sus scrofa; Swine; Transforming Growth Factor beta/genetics; Transforming Growth Factor beta/immunology; Vaccines, Inactivated/administration & dosage; Vaccines, Inactivated/chemistry; Vaccines, Inactivated/immunology; Viral Vaccines/administration & dosage; Viral Vaccines/chemistry; Viral Vaccines/genetics

Key words

Killed PRRSV vaccine; Mucosal immune response; PLGA nanoparticles; PRRS virus; Protection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Porcine respiratory and reproductive syndrome virus / Porcine Reproductive and Respiratory Syndrome Limits: Animals Language: En Journal: Vet Microbiol Year: 2013 Document type: Article Affiliation country: United States Country of publication: Netherlands

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