The water-soluble inclusion complex of ilexgenin A with ß-cyclodextrin polymer--a novel lipid-lowering drug candidate.

Liu, Chang; Zhang, Wang; Wang, Qiang; Sun, Yun; Diao, Guo-wang

Liu, Chang; Zhang, Wang; Wang, Qiang; Sun, Yun; Diao, Guo-wang.

Affiliation

Liu C; College of Medicine, Yangzhou University, 11 Huaihai Rd, Jiangsu Province, Yangzhou, 225002, Jiangsu, PR China.

Org Biomol Chem ; 11(30): 4993-9, 2013 Aug 14.

Article in En | MEDLINE | ID: mdl-23783808

Subject(s)

Hyperlipidemias/drug therapy; Hypolipidemic Agents/pharmacology; Polymers/pharmacology; Triterpenes/pharmacology; beta-Cyclodextrins/pharmacology; Animals; Cholesterol/blood; Disease Models, Animal; Hyperlipidemias/blood; Hyperlipidemias/metabolism; Hypolipidemic Agents/blood; Hypolipidemic Agents/chemistry; Mice; Mice, Inbred C57BL; Molecular Conformation; Polymers/administration & dosage; Polymers/chemistry; Solubility; Triterpenes/blood; Triterpenes/chemistry; Water/chemistry; beta-Cyclodextrins/blood; beta-Cyclodextrins/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Triterpenes / Beta-Cyclodextrins / Hyperlipidemias / Hypolipidemic Agents Limits: Animals Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Document type: Article Country of publication: United kingdom

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