A novel genetic locus modulates infarct volume independently of the extent of collateral circulation.

Chu, Pei-Lun; Keum, Sehoon; Marchuk, Douglas A

Chu, Pei-Lun; Keum, Sehoon; Marchuk, Douglas A.

Affiliation

Chu PL; University Program in Genetics and Genomics and the Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.

Physiol Genomics ; 45(17): 751-63, 2013 Sep 03.

Article in En | MEDLINE | ID: mdl-23800850

Subject(s)

Brain Ischemia/genetics; Brain Ischemia/pathology; Collateral Circulation/genetics; Quantitative Trait Loci; Animals; Brain Infarction/genetics; Brain Infarction/pathology; Chromosome Mapping; Disease Models, Animal; Genetic Linkage; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatases, Non-Receptor/genetics; Scavenger Receptors, Class A/genetics

Key words

collateral circulation; ischemic stroke; quantitative trait locus; stroke genetics; transgressive segregation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Ischemia / Collateral Circulation / Quantitative Trait Loci Type of study: Prognostic_studies Limits: Animals Language: En Journal: Physiol Genomics Journal subject: BIOLOGIA MOLECULAR Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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