Features to validate cerebral toxoplasmosis.
Rev Soc Bras Med Trop
; 46(3): 373-6, 2013.
Article
in En
| MEDLINE
| ID: mdl-23856881
INTRODUCTION: Neurotoxoplasmosis (NT) sometimes manifests unusual characteristics. METHODS: We analyzed 85 patients with NT and AIDS according to clinical, cerebrospinal fluid, cranial magnetic resonance, and polymerase chain reaction (PCR) characteristics. RESULTS: In 8.5%, focal neurological deficits were absent and 16.4% had single cerebral lesions. Increased sensitivity of PCR for Toxoplasma gondii DNA in the central nervous system was associated with pleocytosis and presence of >4 encephalic lesions. CONCLUSIONS: Patients with NT may present without focal neurological deficit and NT may occur with presence of a single cerebral lesion. Greater numbers of lesions and greater cellularity in cerebrospinal fluid improve the sensitivity of PCR to T gondii.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Toxoplasmosis, Cerebral
/
AIDS-Related Opportunistic Infections
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Rev Soc Bras Med Trop
Year:
2013
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil