NPM-RAR, not the RAR-NPM reciprocal t(5;17)(q35;q21) acute promyelocytic leukemia fusion protein, inhibits myeloid differentiation.

Pollock, Sheri L; Rush, Elizabeth A; Redner, Robert L

Pollock, Sheri L; Rush, Elizabeth A; Redner, Robert L.

Affiliation

Pollock SL; Department of Medicine and University of Pittsburgh Cancer Institute, University of Pittsburgh , Pittsburgh, PA , USA.

Leuk Lymphoma ; 55(6): 1383-7, 2014 Jun.

Article in En | MEDLINE | ID: mdl-23927396

Subject(s)

Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 5; Leukemia, Promyelocytic, Acute/genetics; Leukemia, Promyelocytic, Acute/pathology; Oncogene Proteins, Fusion/genetics; Translocation, Genetic; Animals; Cell Differentiation/genetics; Cell Line, Tumor; Gene Expression; Humans; Neoplasm Grading

Key words

Acute promyelocytic leukemia; NPMRAR; RARNPM; U937; differentiation; nucleophosmin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Chromosomes, Human, Pair 5 / Chromosomes, Human, Pair 17 / Leukemia, Promyelocytic, Acute / Oncogene Proteins, Fusion Limits: Animals / Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States

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