miR-105 inhibits prostate tumour growth by suppressing CDK6 levels.

Honeywell, D Rice; Cabrita, Miguel A; Zhao, Huijun; Dimitroulakos, Jim; Addison, Christina L

Honeywell, D Rice; Cabrita, Miguel A; Zhao, Huijun; Dimitroulakos, Jim; Addison, Christina L.

Affiliation

Honeywell DR; Cancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

PLoS One ; 8(8): e70515, 2013.

Article in En | MEDLINE | ID: mdl-23950948

Subject(s)

Cell Proliferation; Cyclin-Dependent Kinase 6/genetics; Gene Expression Regulation, Neoplastic; MicroRNAs/genetics; Prostatic Neoplasms/genetics; Tumor Burden/genetics; 3' Untranslated Regions/genetics; Animals; Apoptosis/genetics; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Movement/genetics; Cell Survival/genetics; Cyclin-Dependent Kinase 6/metabolism; Humans; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/pathology; Reverse Transcriptase Polymerase Chain Reaction; Transcriptome; Transplantation, Heterologous

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Gene Expression Regulation, Neoplastic / MicroRNAs / Tumor Burden / Cell Proliferation / Cyclin-Dependent Kinase 6 Limits: Animals / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Canada Country of publication: United States

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