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Discovery of siRNA lipid nanoparticles to transfect suspension leukemia cells and provide in vivo delivery capability.
He, Wei; Bennett, Michael J; Luistro, Leopoldo; Carvajal, Daisy; Nevins, Thomas; Smith, Melissa; Tyagi, Gaurav; Cai, James; Wei, Xin; Lin, Tai-An; Heimbrook, David C; Packman, Kathryn; Boylan, John F.
Affiliation
  • He W; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA; Current Addresses: Early Discovery, AbbVie Inc., North Chicago, Illinois, USA (W.H.); Monsanto, Davis, California, USA (M.J.B.); Discovery Oncology, Celgene, San Diego, California, USA (J.F.B.). Electronic address: whe@abbvie.com.
  • Bennett MJ; PARD, Hoffmann-La Roche Inc., Nutley, New Jersey, USA; Current Addresses: Early Discovery, AbbVie Inc., North Chicago, Illinois, USA (W.H.); Monsanto, Davis, California, USA (M.J.B.); Discovery Oncology, Celgene, San Diego, California, USA (J.F.B.).
  • Luistro L; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Carvajal D; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Nevins T; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Smith M; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Tyagi G; Non-clinical Safety, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Cai J; pRED Informatics, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Wei X; pRED Informatics, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Lin TA; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Heimbrook DC; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Packman K; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA.
  • Boylan JF; Discovery Oncology, Hoffmann-La Roche Inc., Nutley, New Jersey, USA; Current Addresses: Early Discovery, AbbVie Inc., North Chicago, Illinois, USA (W.H.); Monsanto, Davis, California, USA (M.J.B.); Discovery Oncology, Celgene, San Diego, California, USA (J.F.B.). Electronic address: jboylan@celgene.
Mol Ther ; 22(2): 359-370, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24002693
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transfection / Gene Transfer Techniques / RNA, Small Interfering / Nanoparticles / Lipids Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2014 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transfection / Gene Transfer Techniques / RNA, Small Interfering / Nanoparticles / Lipids Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2014 Document type: Article Country of publication: United States