Reinterpreting the mechanism of inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by D-cycloserine.

Prosser, Gareth A; de Carvalho, Luiz Pedro S

Prosser, Gareth A; de Carvalho, Luiz Pedro S.

Affiliation

Prosser GA; Mycobacterial Research Division, MRC National Institute for Medical Research , The Ridgeway, Mill Hill, London NW7 1AA, U.K.

Biochemistry ; 52(40): 7145-9, 2013 Oct 08.

Article in En | MEDLINE | ID: mdl-24033232

Subject(s)

Cycloserine/pharmacology; Enzyme Inhibitors/pharmacology; Peptide Synthases/antagonists & inhibitors; Binding Sites; Kinetics; Mycobacterium tuberculosis/enzymology; Protein Binding; Stereoisomerism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Synthases / Cycloserine / Enzyme Inhibitors Language: En Journal: Biochemistry Year: 2013 Document type: Article Affiliation country: United kingdom Country of publication: United States

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