HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations.

Jacobs, Michelle M; Murray, Jacinta; Byrd, Desiree A; Hurd, Yasmin L; Morgello, Susan

Jacobs, Michelle M; Murray, Jacinta; Byrd, Desiree A; Hurd, Yasmin L; Morgello, Susan.

J Neurovirol ; 19(5): 495-504, 2013 Oct.

Article in En | MEDLINE | ID: mdl-24078558

Subject(s)

Cognition Disorders/genetics; HIV Infections/genetics; Polymorphism, Genetic; Receptors, Dopamine D1/genetics; Receptors, Dopamine D2/genetics; Substance-Related Disorders/genetics; Adult; Black or African American; Cocaine-Related Disorders/psychology; Cognition Disorders/ethnology; Cognition Disorders/physiopathology; Cognition Disorders/psychology; Cohort Studies; Female; Gene Expression; HIV/pathogenicity; HIV/physiology; HIV Infections/ethnology; HIV Infections/physiopathology; HIV Infections/psychology; Humans; Male; Memory/drug effects; Middle Aged; Neuropsychological Tests; Opioid-Related Disorders/psychology; Receptors, Dopamine D1/metabolism; Receptors, Dopamine D2/metabolism; Regression Analysis; Risk Factors; Substance-Related Disorders/ethnology; Substance-Related Disorders/physiopathology; Substance-Related Disorders/psychology; Task Performance and Analysis; White People

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / HIV Infections / Receptors, Dopamine D2 / Receptors, Dopamine D1 / Cognition Disorders / Substance-Related Disorders Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Neurovirol Journal subject: NEUROLOGIA / VIROLOGIA Year: 2013 Document type: Article Country of publication: United States

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