Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization.

Tesio, Melania; Oser, Gabriela M; Baccelli, Irène; Blanco-Bose, William; Wu, Hong; Göthert, Joachim R; Kogan, Scott C; Trumpp, Andreas

Tesio, Melania; Oser, Gabriela M; Baccelli, Irène; Blanco-Bose, William; Wu, Hong; Göthert, Joachim R; Kogan, Scott C; Trumpp, Andreas.

Affiliation

Tesio M; Deutsches Krebsforschungszentrum (DKFZ), D-69120 Heidelberg, Germany.

J Exp Med ; 210(11): 2337-49, 2013 Oct 21.

Article in En | MEDLINE | ID: mdl-24127490

Subject(s)

Bone Marrow/enzymology; Granulocyte Colony-Stimulating Factor/metabolism; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells/cytology; Hematopoietic Stem Cells/enzymology; PTEN Phosphohydrolase/deficiency; Alleles; Animals; Cytokines/metabolism; Gene Deletion; Granulocyte Colony-Stimulating Factor/deficiency; Integrases/metabolism; Mice; Myeloproliferative Disorders/enzymology; Myeloproliferative Disorders/pathology; PTEN Phosphohydrolase/metabolism; Phenotype; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/enzymology; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology; Proto-Oncogene Proteins c-akt/metabolism; Spleen/metabolism; Spleen/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Hematopoietic Stem Cells / Granulocyte Colony-Stimulating Factor / Hematopoietic Stem Cell Mobilization / PTEN Phosphohydrolase Limits: Animals Language: En Journal: J Exp Med Year: 2013 Document type: Article Affiliation country: Germany Country of publication: United States

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