The development of Wy-41,195, an orally effective antiallergic drug in animal models.

Lewis, A J; Carlson, R P; Forster, T J; Chang, J; Hand, J M; Undem, B J; Buckner, C K; Tio, C; Sisenwine, S F; Daniel, W C

Lewis, A J; Carlson, R P; Forster, T J; Chang, J; Hand, J M; Undem, B J; Buckner, C K; Tio, C; Sisenwine, S F; Daniel, W C.

Agents Actions ; 18(3-4): 306-12, 1986 Jun.

Article in En | MEDLINE | ID: mdl-2428218

Subject(s)

Amino Acids; Asthma/drug therapy; Histamine H1 Antagonists/therapeutic use; Oxamic Acid/analogs & derivatives; Administration, Oral; Animals; Disease Models, Animal; Dogs; Guinea Pigs; Histamine Release/drug effects; Humans; Hypersensitivity, Immediate; Kinetics; Lung/drug effects; Lung/immunology; Mast Cells/drug effects; Mast Cells/physiology; Oxamic Acid/metabolism; Oxamic Acid/pharmacology; Oxamic Acid/therapeutic use; Rats; Skin/drug effects; Skin/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Oxamic Acid / Asthma / Amino Acids / Histamine H1 Antagonists Limits: Animals / Humans Language: En Journal: Agents Actions Year: 1986 Document type: Article Country of publication: Switzerland

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