KAT5 and KAT6B are in positive regulation on cell proliferation of prostate cancer through PI3K-AKT signaling.

He, Wei; Zhang, Min-Guang; Wang, Xiao-Jing; Zhong, Shan; Shao, Yuan; Zhu, Yu; Shen, Zhou-Jun

He, Wei; Zhang, Min-Guang; Wang, Xiao-Jing; Zhong, Shan; Shao, Yuan; Zhu, Yu; Shen, Zhou-Jun.

Affiliation

He W; Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University Shanghai, China.

Int J Clin Exp Pathol ; 6(12): 2864-71, 2013.

Article in En | MEDLINE | ID: mdl-24294372

Subject(s)

Cell Proliferation; Histone Acetyltransferases/metabolism; Phosphatidylinositol 3-Kinase/metabolism; Prostatic Neoplasms/enzymology; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; Cell Line, Tumor; Epigenesis, Genetic; Extracellular Signal-Regulated MAP Kinases/metabolism; Gene Expression Profiling/methods; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases/genetics; Humans; Lysine Acetyltransferase 5; Male; Oligonucleotide Array Sequence Analysis; Phosphorylation; Prostatic Neoplasms/genetics; Prostatic Neoplasms/pathology; RNA Interference; Transfection

Key words

KAT5; KAT6B; PI3K-AKT signaling; Prostate cancer; RNAi screening; histone modifications

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Signal Transduction / Cell Proliferation / Histone Acetyltransferases / Proto-Oncogene Proteins c-akt / Phosphatidylinositol 3-Kinase Limits: Humans / Male Language: En Journal: Int J Clin Exp Pathol Journal subject: PATOLOGIA Year: 2013 Document type: Article Affiliation country: China Country of publication: United States

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