Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.

Ryan, Sean O; Leal, Sixto M; Abbott, Derek W; Pearlman, Eric; Cobb, Brian A

Ryan, Sean O; Leal, Sixto M; Abbott, Derek W; Pearlman, Eric; Cobb, Brian A.

Affiliation

Ryan SO; Department of Pathology.

Glycobiology ; 24(3): 262-71, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24310166

Subject(s)

Antigen Presentation; Lymphocyte Activation; Myeloid Cells/immunology; N-Acetylglucosaminyltransferases/metabolism; T-Lymphocytes/immunology; Animals; Antigen-Presenting Cells/immunology; Gene Deletion; Mice; Mice, Inbred C57BL; N-Acetylglucosaminyltransferases/genetics; Polysaccharides/metabolism; Toll-Like Receptor 2/metabolism

Key words

CDG-IIa; MHC class II; T lymphocyte; antigen presentation; glycoantigen

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / T-Lymphocytes / N-Acetylglucosaminyltransferases / Antigen Presentation / Myeloid Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Glycobiology Journal subject: BIOQUIMICA Year: 2014 Document type: Article Country of publication: United kingdom

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