A novel oncolytic viral therapy and imaging technique for gastric cancer using a genetically engineered vaccinia virus carrying the human sodium iodide symporter.

Jun, Kyong-Hwa; Gholami, Sepideh; Song, Tae-Jin; Au, Joyce; Haddad, Dana; Carson, Joshua; Chen, Chun-Hao; Mojica, Kelly; Zanzonico, Pat; Chen, Nanhai G; Zhang, Qian; Szalay, Aladar; Fong, Yuman

Jun, Kyong-Hwa; Gholami, Sepideh; Song, Tae-Jin; Au, Joyce; Haddad, Dana; Carson, Joshua; Chen, Chun-Hao; Mojica, Kelly; Zanzonico, Pat; Chen, Nanhai G; Zhang, Qian; Szalay, Aladar; Fong, Yuman.

Affiliation

Fong Y; Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA. fongy@mskcc.org.

J Exp Clin Cancer Res ; 33: 2, 2014 Jan 02.

Article in En | MEDLINE | ID: mdl-24383569

Subject(s)

Oncolytic Viruses/genetics; Stomach Neoplasms/therapy; Symporters/genetics; Vaccinia virus/genetics; Animals; Cell Line, Tumor; Female; Genetic Engineering; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Oncolytic Virotherapy; Radionuclide Imaging; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Stomach Neoplasms/diagnostic imaging; Stomach Neoplasms/pathology; Tumor Burden; Virus Replication

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Vaccinia virus / Symporters / Oncolytic Viruses Type of study: Screening_studies Limits: Animals / Female / Humans Language: En Journal: J Exp Clin Cancer Res Year: 2014 Document type: Article Country of publication: United kingdom

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