Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria.

Hernández, Jessica Soto; Barreto-Torres, Giselle; Kuznetsov, Andrey V; Khuchua, Zaza; Javadov, Sabzali

Hernández, Jessica Soto; Barreto-Torres, Giselle; Kuznetsov, Andrey V; Khuchua, Zaza; Javadov, Sabzali.

Affiliation

Hernández JS; Department of Physiology, School of Medicine, University of Puerto Rico, San Juan, PR, USA.

J Cell Mol Med ; 18(4): 709-20, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24444314

Subject(s)

AMP-Activated Protein Kinases/metabolism; Angiotensin II/administration & dosage; Cardiomegaly/metabolism; Mitochondria/metabolism; Myocytes, Cardiac/metabolism; AMP-Activated Protein Kinases/biosynthesis; Angiotensin II Type 1 Receptor Blockers/administration & dosage; Animals; Cardiomegaly/drug therapy; Cardiomegaly/pathology; Gene Expression Regulation/drug effects; Losartan/administration & dosage; Metformin/administration & dosage; Mitochondria/drug effects; Mitochondria/pathology; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/pathology; Nitric Oxide Synthase Type III/metabolism; Rats; Receptor, Angiotensin, Type 1/biosynthesis; Signal Transduction; Sirtuin 1/metabolism; Tumor Suppressor Protein p53/metabolism

Key words

AMP kinase; angiotensin II receptors; hypertrophy; metformin; mitochondria

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin II / Cardiomegaly / Myocytes, Cardiac / AMP-Activated Protein Kinases / Mitochondria Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2014 Document type: Article Affiliation country: United States Country of publication: United kingdom

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