Development and characterization of a ricinoleic acid poloxamer gel system for transdermal eyelid delivery.

Boddu, Sai H S; Bonam, Sindhu Prabha; Jung, Rose

Boddu, Sai H S; Bonam, Sindhu Prabha; Jung, Rose.

Affiliation

Boddu SH; Department of Pharmacy Practice, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo , Toledo, OH , USA.

Drug Dev Ind Pharm ; 41(4): 605-12, 2015 Apr.

Article in En | MEDLINE | ID: mdl-24517574

Subject(s)

Anti-Bacterial Agents/administration & dosage; Anti-Inflammatory Agents/administration & dosage; Drug Delivery Systems; Excipients/chemistry; Lecithins/chemistry; Poloxamer/chemistry; Ricinoleic Acids/chemistry; Abattoirs; Administration, Cutaneous; Animals; Anti-Bacterial Agents/analysis; Anti-Bacterial Agents/metabolism; Anti-Bacterial Agents/pharmacology; Anti-Inflammatory Agents/analysis; Anti-Inflammatory Agents/metabolism; Cattle; Dexamethasone/administration & dosage; Dexamethasone/analysis; Dexamethasone/metabolism; Drug Combinations; Drug Compounding; Drug Liberation; Eye Infections, Bacterial/drug therapy; Eye Infections, Bacterial/immunology; Eyelids; Gels; Humans; Pseudomonas aeruginosa/drug effects; Pseudomonas aeruginosa/growth & development; Skin Absorption; Tobramycin/administration & dosage; Tobramycin/analysis; Tobramycin/metabolism; Tobramycin/pharmacology; Viscosity

Key words

Eyelids; Pluronic F127; lecithin; pluronic lecithin organogel; ricinoleic acid; transdermal

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ricinoleic Acids / Drug Delivery Systems / Poloxamer / Excipients / Lecithins / Anti-Inflammatory Agents / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: Drug Dev Ind Pharm Year: 2015 Document type: Article Affiliation country: United States

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