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Evidence of Clonal Expansion in the Genome of a Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolate from Peru.
Galarza, M; Tarazona, D; Borda, V; Agapito, J C; Guio, H.
Affiliation
  • Galarza M; Laboratorio de Biotecnología y Biología Molecular, Instituto Nacional de Salud, Lima, Peru.
Genome Announc ; 2(1)2014 Feb 27.
Article in En | MEDLINE | ID: mdl-24578270
We report the genome sequence of Mycobacterium tuberculosis INS-MDR from Peru, a multidrug-resistant tuberculosis (MDR-TB) and Latin American-Mediterranean (LAM) lineage strain. Our analysis showed mutations related to drug resistance in the rpoB (D516V), katG (S315T), kasA (G269S), and pncA (Q10R) genes. Our evidence suggests that INS-MDR may be a clonal expansion related to the African strain KZN 1435.

Full text: 1 Collection: 01-internacional Database: MEDLINE Country/Region as subject: America do sul / Peru Language: En Journal: Genome Announc Year: 2014 Document type: Article Affiliation country: Peru Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Country/Region as subject: America do sul / Peru Language: En Journal: Genome Announc Year: 2014 Document type: Article Affiliation country: Peru Country of publication: United States