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Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.
Huser, Camille A; Gilroy, Kathryn L; de Ridder, Jeroen; Kilbey, Anna; Borland, Gillian; Mackay, Nancy; Jenkins, Alma; Bell, Margaret; Herzyk, Pawel; van der Weyden, Louise; Adams, David J; Rust, Alistair G; Cameron, Ewan; Neil, James C.
Affiliation
  • Huser CA; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Gilroy KL; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • de Ridder J; Delft Bioinformatics Lab, Faculty of EEMCS, TU Delft, Delft, The Netherlands.
  • Kilbey A; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Borland G; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Mackay N; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Jenkins A; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Bell M; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Herzyk P; Glasgow Polyomics, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • van der Weyden L; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
  • Adams DJ; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
  • Rust AG; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
  • Cameron E; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Neil JC; Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
PLoS Genet ; 10(2): e1004167, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24586197

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mutagenesis, Insertional / Tumor Suppressor Protein p53 / Genes, myb / Lymphoma / Moloney murine leukemia virus Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2014 Document type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mutagenesis, Insertional / Tumor Suppressor Protein p53 / Genes, myb / Lymphoma / Moloney murine leukemia virus Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2014 Document type: Article Affiliation country: United kingdom