The bone regenerative effects of fucosterol in in vitro and in vivo models of postmenopausal osteoporosis.

Lee, Don-Gil; Park, Sang-Yong; Chung, Won-Seok; Park, Jae-Hee; Shin, Heon-Sub; Hwang, Eunson; Kim, In-Ho; Yi, Tae-Hoo

Lee, Don-Gil; Park, Sang-Yong; Chung, Won-Seok; Park, Jae-Hee; Shin, Heon-Sub; Hwang, Eunson; Kim, In-Ho; Yi, Tae-Hoo.

Affiliation

Lee DG; Department of Oriental Medicinal Materials & Processing, College of Life Science, Kyung Hee University, Gyeonggi-do, Republic of Korea.

Mol Nutr Food Res ; 58(6): 1249-57, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24604889

Subject(s)

Bone Regeneration/drug effects; Osteoporosis, Postmenopausal/drug therapy; Stigmasterol/analogs & derivatives; Administration, Oral; Alkaline Phosphatase/metabolism; Animals; Bone Density/drug effects; Bone Resorption/drug therapy; Cell Differentiation/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Collagen Type I/blood; Disease Models, Animal; Female; Femur/drug effects; Femur/metabolism; Humans; Osteoblasts/cytology; Osteoblasts/drug effects; Osteoblasts/metabolism; Osteocalcin/blood; Osteoclasts/cytology; Osteoclasts/drug effects; Osteoclasts/metabolism; Osteogenesis/drug effects; Ovariectomy; Peptides/blood; Rats; Rats, Sprague-Dawley; Stigmasterol/pharmacology

Key words

Brown sea weed; Fucosterol; Osteoblastogenesis; Osteoporosis; Ovariectomized rat

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stigmasterol / Bone Regeneration / Osteoporosis, Postmenopausal Limits: Animals / Female / Humans Language: En Journal: Mol Nutr Food Res Journal subject: CIENCIAS DA NUTRICAO Year: 2014 Document type: Article Country of publication: Germany

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