Defining the genomic landscape of head and neck cancers through next-generation sequencing.

Rizzo, G; Black, M; Mymryk, J S; Barrett, J W; Nichols, A C

Rizzo, G; Black, M; Mymryk, J S; Barrett, J W; Nichols, A C.

Affiliation

Rizzo G; Department of Otolaryngology Head & Neck Surgery, Western University, London, ON, Canada; London Regional Cancer Program, London, ON, Canada; Lawson Health Research Institute, London, ON, Canada; Department of Anatomy and Cell Biology, Western University, London, ON, Canada.

Oral Dis ; 21(1): e11-24, 2015 Jan.

Article in En | MEDLINE | ID: mdl-24725020

Subject(s)

DNA, Neoplasm/genetics; Head and Neck Neoplasms/genetics; High-Throughput Nucleotide Sequencing; Carcinoma, Squamous Cell/genetics; Head and Neck Neoplasms/drug therapy; High-Throughput Nucleotide Sequencing/methods; Humans; Molecular Targeted Therapy

Key words

E6; E7; HPV; NOTCH pathway; PI3K/Akt pathway; cell cycle control; genomics; head and neck cancer; head and neck squamous cell carcinoma; human papillomavirus; next-generation sequencing; sequencing; therapeutic targets

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / High-Throughput Nucleotide Sequencing / Head and Neck Neoplasms Limits: Humans Language: En Journal: Oral Dis Journal subject: ODONTOLOGIA Year: 2015 Document type: Article Affiliation country: Canada Country of publication: Denmark

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