Spi6 protects alloreactive CD4(+) but not CD8 (+) memory T cell from granzyme B attack by double-negative T regulatory cell.

Su, Y; Jevnikar, A M; Huang, X; Lian, D; Zhang, Z -X

Su, Y; Jevnikar, A M; Huang, X; Lian, D; Zhang, Z -X.

Am J Transplant ; 14(3): 580-93, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24730048

Subject(s)

CD4-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/immunology; Granzymes/physiology; Immunologic Memory/immunology; Membrane Proteins/physiology; Serpins/physiology; Skin Transplantation; T-Lymphocytes, Regulatory/immunology; Animals; Blotting, Western; Fas Ligand Protein/physiology; Flow Cytometry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Pore Forming Cytotoxic Proteins/physiology; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Serpins / Skin Transplantation / T-Lymphocytes, Regulatory / CD8-Positive T-Lymphocytes / Granzymes / Immunologic Memory / Membrane Proteins Limits: Animals Language: En Journal: Am J Transplant Journal subject: TRANSPLANTE Year: 2014 Document type: Article

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