Pharmacokinetics and pharmacodynamics of recombinant human granulocyte-colony stimulating factor after intravenous and subcutaneous administration in the rat.

Tanaka, H; Okada, Y; Kawagishi, M; Tokiwa, T

Tanaka, H; Okada, Y; Kawagishi, M; Tokiwa, T.

Affiliation

Tanaka H; Pharmaceutical Laboratory, Kirin Brewery Co., Ltd., Gunma, Japan.

J Pharmacol Exp Ther ; 251(3): 1199-203, 1989 Dec.

Article in En | MEDLINE | ID: mdl-2481032

Subject(s)

Colony-Stimulating Factors/pharmacokinetics; Animals; Colony-Stimulating Factors/administration & dosage; Colony-Stimulating Factors/pharmacology; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis/drug effects; Injections, Intravenous; Injections, Subcutaneous; Metabolic Clearance Rate; Mice; Mice, Inbred C3H; Neutrophils/drug effects; Rats; Rats, Inbred Strains; Recombinant Proteins/administration & dosage; Recombinant Proteins/pharmacokinetics; Recombinant Proteins/pharmacology; Thymidine/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Colony-Stimulating Factors Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 1989 Document type: Article Affiliation country: Japan Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links