Discovery of hapten-specific scFv from a phage display library and applications for HER2-positive tumor imaging.

Kim, Hye-Yeong; Wang, Xiaolei; Wahlberg, Brendon; Edwards, W Barry

Kim, Hye-Yeong; Wang, Xiaolei; Wahlberg, Brendon; Edwards, W Barry.

Affiliation

Kim HY; Molecular Imaging Laboratory, Department of Radiology, University of Pittsburgh , 100 Technology Drive, Pittsburgh, Pennsylvania 15219, United States.

Bioconjug Chem ; 25(7): 1311-22, 2014 Jul 16.

Article in En | MEDLINE | ID: mdl-24898150

Subject(s)

Breast Neoplasms/pathology; Haptens/immunology; Molecular Imaging/methods; Peptide Fragments/immunology; Peptide Library; Receptor, ErbB-2/immunology; Single-Chain Antibodies/immunology; Animals; Blotting, Western; Breast Neoplasms/immunology; Breast Neoplasms/metabolism; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; Fluorescent Dyes; Haptens/metabolism; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Peptide Fragments/metabolism; Receptor, ErbB-2/metabolism; Single-Chain Antibodies/metabolism; Spectroscopy, Near-Infrared; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Breast Neoplasms / Receptor, ErbB-2 / Peptide Library / Single-Chain Antibodies / Molecular Imaging / Haptens Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States

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