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Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies.
Llabrés, Salomé; García-Ratés, Sara; Cristóbal-Lecina, Edgar; Riera, Antoni; Borrell, José Ignacio; Camarasa, Jorge; Pubill, David; Luque, F Javier; Escubedo, Elena.
Affiliation
  • Llabrés S; Department of Physical Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, Campus de l'Alimentació Torribera, University of Barcelona, Avda. Prat de la Riba 171, Santa Coloma de Gramenet, E-08921 Barcelona, Spain.
  • García-Ratés S; Department of Pharmacology and Therapeutic Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, University of Barcelona, Nucli Univ. Pedralbes, E-08028 Barcelona, Spain.
  • Cristóbal-Lecina E; Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10, 08028 Barcelona, Spain.
  • Riera A; Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10, 08028 Barcelona, Spain.
  • Borrell JI; IQS School of Engineering, Universitat Ramon Llull, Via Augusta 390, E-08017 Barcelona, Spain.
  • Camarasa J; Department of Pharmacology and Therapeutic Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, University of Barcelona, Nucli Univ. Pedralbes, E-08028 Barcelona, Spain.
  • Pubill D; Department of Pharmacology and Therapeutic Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, University of Barcelona, Nucli Univ. Pedralbes, E-08028 Barcelona, Spain.
  • Luque FJ; Department of Physical Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, Campus de l'Alimentació Torribera, University of Barcelona, Avda. Prat de la Riba 171, Santa Coloma de Gramenet, E-08921 Barcelona, Spain.
  • Escubedo E; Department of Pharmacology and Therapeutic Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, University of Barcelona, Nucli Univ. Pedralbes, E-08028 Barcelona, Spain. Electronic address: eescubedo@ub.edu.
Eur J Med Chem ; 81: 35-46, 2014 Jun 23.
Article in En | MEDLINE | ID: mdl-24942641
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Nicotinic / 3,4-Methylenedioxyamphetamine Limits: Animals Language: En Journal: Eur J Med Chem Year: 2014 Document type: Article Affiliation country: Spain Country of publication: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Nicotinic / 3,4-Methylenedioxyamphetamine Limits: Animals Language: En Journal: Eur J Med Chem Year: 2014 Document type: Article Affiliation country: Spain Country of publication: France