oxLDL induces injury and defenestration of human liver sinusoidal endothelial cells via LOX1.

Zhang, Qi; Liu, Jing; Liu, Jia; Huang, Wenhui; Tian, Limin; Quan, Jinxing; Wang, Yunfang; Niu, Ruilan

Zhang, Qi; Liu, Jing; Liu, Jia; Huang, Wenhui; Tian, Limin; Quan, Jinxing; Wang, Yunfang; Niu, Ruilan.

Affiliation

Zhang Q; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.
Liu J; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China liujingwelcome@126.com.
Liu J; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.
Huang W; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.
Tian L; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.
Quan J; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.
Wang Y; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.
Niu R; The First Clinical College of Lanzhou University730000 Lanzhou, Gansu, ChinaDepartment of EndocrinologyGansu Provincial Hospital, 204 West Donggang Road, 730000 Lanzhou, Gansu, China.

J Mol Endocrinol ; 53(2): 281-93, 2014 Oct.

Article in En | MEDLINE | ID: mdl-25057109

Subject(s)

Endothelial Cells/metabolism; Lipoproteins, LDL/metabolism; Liver/metabolism; Scavenger Receptors, Class E/metabolism; Caveolin 1/genetics; Caveolin 1/metabolism; Endothelial Cells/drug effects; Endothelial Cells/ultrastructure; Endothelin-1/genetics; Endothelin-1/metabolism; Endothelium, Vascular/drug effects; Endothelium, Vascular/metabolism; Female; Gene Expression Regulation/drug effects; Humans; Lipoproteins, LDL/pharmacology; Lipoproteins, LDL/toxicity; Middle Aged; NF-kappa B/metabolism; Nitric Oxide Synthase Type III/metabolism; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; RNA Interference; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reactive Oxygen Species/metabolism; Scavenger Receptors, Class E/genetics

Key words

defenestration; endothelial injury; human liver sinusoidal endothelial cells; lectin-like oxLDL receptor 1; oxidised LDL

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelial Cells / Scavenger Receptors, Class E / Lipoproteins, LDL / Liver Limits: Female / Humans / Middle aged Language: En Journal: J Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 2014 Document type: Article Affiliation country: China Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google