Effect of recombinant human keratinocyte growth factor in inducing Ras-Raf-Erk pathway-mediated cell proliferation in emphysematous mice lung.

Muyal, Jai Prakash; Kotnala, Sudhir; Bhardwaj, Harsh; Tyagi, Amit

Muyal, Jai Prakash; Kotnala, Sudhir; Bhardwaj, Harsh; Tyagi, Amit.

Affiliation

Muyal JP; School of Biotechnology, Gautam Buddha University , Greater Noida, Uttar Pradesh , India and.

Inhal Toxicol ; 26(13): 761-71, 2014 Nov.

Article in En | MEDLINE | ID: mdl-25296878

Subject(s)

Cell Proliferation/physiology; Fibroblast Growth Factor 7/pharmacology; MAP Kinase Signaling System/drug effects; Pulmonary Emphysema/drug therapy; Animals; Blotting, Western; Cell Proliferation/drug effects; Disease Models, Animal; Humans; Lung/pathology; MAP Kinase Signaling System/physiology; Male; Mice; Mice, Inbred C57BL; Pulmonary Alveoli/drug effects; Pulmonary Alveoli/physiology; Pulmonary Emphysema/pathology; Pulmonary Emphysema/physiopathology; Receptor, Fibroblast Growth Factor, Type 2/drug effects; Recombinant Proteins/pharmacology

Key words

Alveolar regeneration; RasRafErk pathway; emphysema; rHuKGF

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Emphysema / MAP Kinase Signaling System / Cell Proliferation / Fibroblast Growth Factor 7 Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Inhal Toxicol Journal subject: TOXICOLOGIA Year: 2014 Document type: Article

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