LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses.

Wang, Shao-hua; Huang, Yan; Yuan, Yang; Xia, Wen-qing; Wang, Pin; Huang, Rong

Wang, Shao-hua; Huang, Yan; Yuan, Yang; Xia, Wen-qing; Wang, Pin; Huang, Rong.

Affiliation

Wang SH; Department of Endocrinology, ZhongDa Hospital of Southeast University, No,87 DingJiaQiao Road, Nanjing 210009, PR China. gyjwsh@126.com.

Lipids Health Dis ; 13: 175, 2014 Nov 20.

Article in En | MEDLINE | ID: mdl-25413784

Subject(s)

Apoptosis; CA1 Region, Hippocampal/metabolism; Cognition Disorders/genetics; Receptors, LDL/genetics; Synapses/metabolism; Animals; Apoptosis Regulatory Proteins/genetics; Apoptosis Regulatory Proteins/metabolism; CA1 Region, Hippocampal/pathology; Cognition; Gene Expression; Male; Maze Learning; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL/metabolism; Synapses/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Receptors, LDL / Apoptosis / Cognition Disorders / CA1 Region, Hippocampal Limits: Animals Language: En Journal: Lipids Health Dis Journal subject: BIOQUIMICA / METABOLISMO Year: 2014 Document type: Article Country of publication: United kingdom

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