Association of drug exposure with toxicity and clinical response in metastatic renal cell carcinoma patients receiving an attenuated dosing regimen of sunitinib.

Teo, Yi Ling; Chue, Xiu Ping; Chau, Noan Minh; Tan, Min-Han; Kanesvaran, Ravindran; Wee, Hwee Lin; Ho, Han Kiat; Chan, Alexandre

Teo, Yi Ling; Chue, Xiu Ping; Chau, Noan Minh; Tan, Min-Han; Kanesvaran, Ravindran; Wee, Hwee Lin; Ho, Han Kiat; Chan, Alexandre.

Affiliation

Teo YL; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore, 117543, Singapore.

Target Oncol ; 10(3): 429-37, 2015 Sep.

Article in En | MEDLINE | ID: mdl-25502986

Subject(s)

Carcinoma, Renal Cell/drug therapy; Carcinoma, Renal Cell/pathology; Indoles/administration & dosage; Kidney Neoplasms/drug therapy; Kidney Neoplasms/pathology; Pyrroles/administration & dosage; Aged; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/pharmacokinetics; Antineoplastic Agents/toxicity; Disease Progression; Drug Administration Schedule; Drug Monitoring; Female; Humans; Indoles/pharmacokinetics; Indoles/toxicity; Longitudinal Studies; Male; Middle Aged; Mucositis/chemically induced; Neoplasm Metastasis; Prospective Studies; Pyrroles/pharmacokinetics; Pyrroles/toxicity; Singapore; Sunitinib

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Carcinoma, Renal Cell / Indoles / Kidney Neoplasms Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Target Oncol Journal subject: NEOPLASIAS Year: 2015 Document type: Article Affiliation country: Singapore Country of publication: France

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