Leishmanial sphingolipid induces apoptosis in Sarcoma 180 cancer cells through regulation of tumour growth via angiogenic switchover.

Das, Subhadip; Chatterjee, Nabanita; Bose, Dipayan; Banerjee, Somenath; Jha, Tarun; Saha, Krishna Das

Das, Subhadip; Chatterjee, Nabanita; Bose, Dipayan; Banerjee, Somenath; Jha, Tarun; Saha, Krishna Das.

Affiliation

Das S; Cancer Biology & Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata, West Bengal, 700032, India.

Tumour Biol ; 36(4): 3109-18, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25524576

Subject(s)

Cell Proliferation/drug effects; Neovascularization, Pathologic/drug therapy; Sarcoma 180/drug therapy; Sphingolipids/administration & dosage; Animals; Apoptosis/drug effects; Caspase 3/biosynthesis; Cell Cycle/drug effects; Cell Line, Tumor; Humans; Leishmania donovani/chemistry; Membrane Potential, Mitochondrial/drug effects; Mice; Neovascularization, Pathologic/pathology; Reactive Oxygen Species/metabolism; Sarcoma 180/pathology; Signal Transduction/drug effects; Sphingolipids/chemistry; Sphingolipids/isolation & purification; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma 180 / Sphingolipids / Cell Proliferation / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Tumour Biol Journal subject: NEOPLASIAS Year: 2015 Document type: Article Affiliation country: India Country of publication: Netherlands

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