Controlled Endolysosomal Release of Agents by pH-responsive Polymer Blend Particles.

Zhan, Xi; Tran, Kenny K; Wang, Liguo; Shen, Hong

Zhan, Xi; Tran, Kenny K; Wang, Liguo; Shen, Hong.

Affiliation

Zhan X; Department of Biological Structure, University of Washington School of Medicine, Seattle, WA, 98195, USA.

Pharm Res ; 32(7): 2280-91, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25592550

Subject(s)

Drug Carriers/chemistry; Endosomes/metabolism; Lysosomes/metabolism; Pharmaceutical Preparations/administration & dosage; Polymers/chemistry; Acridine Orange/administration & dosage; Acrylic Resins/chemical synthesis; Acrylic Resins/chemistry; Animals; Cell Line; Cell Membrane Permeability; Drug Carriers/chemical synthesis; Drug Carriers/metabolism; Drug Liberation; Endocytosis; Endosomes/enzymology; Hydrogen-Ion Concentration; Lactic Acid/chemical synthesis; Lactic Acid/chemistry; Lactic Acid/metabolism; Lysosomes/enzymology; Methacrylates/chemical synthesis; Methacrylates/chemistry; Methacrylates/metabolism; Mice; Molecular Weight; Polyglycolic Acid/chemical synthesis; Polyglycolic Acid/chemistry; Polyglycolic Acid/metabolism; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers/chemical synthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Endosomes / Drug Carriers / Pharmaceutical Preparations / Lysosomes Limits: Animals Language: En Journal: Pharm Res Year: 2015 Document type: Article Affiliation country: United States

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