The clinical utility of pharmacological agents that act at serotonin receptors.
J Neuropsychiatry Clin Neurosci
; 1(3): 253-62, 1989.
Article
in En
| MEDLINE
| ID: mdl-2562495
ABSTRACT
The past decade has seen important advances in the clinical utility of serotonergic agents. The putative novel anxiolytic effects of 5-HT1A partial agonists such as buspirone, the antidepressant effects of selective serotonin (5-HT) uptake blockers such as fluoxetine, and the unique and potent antiemetic effects of 5-HT3 antagonists in cancer chemotherapy are excellent examples of the clinical relevance of selective 5-HT receptor agents. The increasing ability to modulate serotonergic neurotransmission through distinct 5-HT receptor subtypes should greatly facilitate the analysis of 5-HT in both normal and abnormal human brain function.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psychotropic Drugs
/
Serotonin Antagonists
/
Serotonin
/
Receptors, Serotonin
/
Synaptic Transmission
/
Neurocognitive Disorders
Limits:
Animals
/
Humans
Language:
En
Journal:
J Neuropsychiatry Clin Neurosci
Journal subject:
NEUROLOGIA
/
PSIQUIATRIA
Year:
1989
Document type:
Article