Self-nanoemulsifying drug delivery system of trans-cinnamic acid: formulation development and pharmacodynamic evaluation in alloxan-induced type 2 diabetic rat model.

Wang, Houyong; Li, Qiang; Deng, Wenwen; Omari-Siaw, E; Wang, Qilong; Wang, Shicheng; Wang, Shengli; Cao, Xia; Xu, Ximing; Yu, Jiangnan

Wang, Houyong; Li, Qiang; Deng, Wenwen; Omari-Siaw, E; Wang, Qilong; Wang, Shicheng; Wang, Shengli; Cao, Xia; Xu, Ximing; Yu, Jiangnan.

Affiliation

Wang H; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu University, Zhenjiang, People's Republic of China.

Drug Dev Res ; 76(2): 82-93, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25847843

Subject(s)

Cinnamates/pharmacokinetics; Diabetes Mellitus, Experimental/drug therapy; Emulsifying Agents/chemistry; Hypoglycemic Agents/pharmacokinetics; Nanocomposites/chemistry; Alloxan; Animals; Cinnamates/administration & dosage; Diabetes Mellitus, Experimental/chemically induced; Drug Delivery Systems/methods; Drug Design; Hypoglycemic Agents/administration & dosage; Male; Nanocomposites/administration & dosage; Nanocomposites/therapeutic use; Rats; Rats, Wistar

Key words

diabetes; hyperglycemia; self-nanoemulsifying drug delivery system; trans-cinnamic acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cinnamates / Emulsifying Agents / Diabetes Mellitus, Experimental / Nanocomposites / Hypoglycemic Agents Limits: Animals Language: En Journal: Drug Dev Res Year: 2015 Document type: Article Country of publication: United States

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