Acetylcholinesterase inhibitory and antioxidant activities of novel symmetric sulfamides derived from phenethylamines.

Aksu, Kadir; Topal, Fevzi; Gulcin, Ilhami; Tümer, Ferhan; Göksu, Süleyman

Aksu, Kadir; Topal, Fevzi; Gulcin, Ilhami; Tümer, Ferhan; Göksu, Süleyman.

Affiliation

Aksu K; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.
Topal F; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.
Gulcin I; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.
Tümer F; Fetal Programming of Diseases Research Chair, Zoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Göksu S; Department of Chemistry, Faculty of Science and Arts, Sutcu Imam University, Kahramanmaras, Turkey.

Arch Pharm (Weinheim) ; 348(6): 446-55, 2015 Jun.

Article in En | MEDLINE | ID: mdl-25914190

Subject(s)

Acetylcholinesterase/metabolism; Antioxidants/chemical synthesis; Antioxidants/pharmacology; Cholinesterase Inhibitors/chemical synthesis; Cholinesterase Inhibitors/pharmacology; Phenethylamines/chemistry; Sulfonamides/chemical synthesis; Sulfonamides/pharmacology; Drug Design; Free Radicals/chemistry; Iron Chelating Agents/chemical synthesis; Iron Chelating Agents/pharmacology; Molecular Structure; Oxidation-Reduction; Reactive Oxygen Species/chemistry; Structure-Activity Relationship

Key words

Acetylcholine esterase; Antioxidant activity; Enzyme inhibition; Phenethylamines; Sulfamide

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenethylamines / Acetylcholinesterase / Sulfonamides / Cholinesterase Inhibitors / Antioxidants Language: En Journal: Arch Pharm (Weinheim) Year: 2015 Document type: Article Affiliation country: Turkey Country of publication: Germany

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