Mass spectrometric approaches to study protein structure and interactions in lyophilized powders.

Moorthy, Balakrishnan S; Iyer, Lavanya K; Topp, Elizabeth M

Moorthy, Balakrishnan S; Iyer, Lavanya K; Topp, Elizabeth M.

Affiliation

Moorthy BS; Department of Industrial and Physical Pharmacy, Purdue University.
Iyer LK; Department of Industrial and Physical Pharmacy, Purdue University.
Topp EM; Department of Industrial and Physical Pharmacy, Purdue University.

J Vis Exp ; (98): 52503, 2015 Apr 14.

Article in En | MEDLINE | ID: mdl-25938927

Subject(s)

Deuterium Exchange Measurement/methods; Mass Spectrometry/methods; Proteins/chemistry; Amides/chemistry; Freeze Drying/methods; Kinetics; Peptides/chemistry; Protein Conformation; Protein Folding; Protein Structure, Secondary

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mass Spectrometry / Proteins / Deuterium Exchange Measurement Type of study: Guideline Language: En Journal: J Vis Exp Year: 2015 Document type: Article Country of publication: United States

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