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Selective late INa inhibition by GS-458967 exerts parallel suppression of catecholamine-induced hemodynamically significant ventricular tachycardia and T-wave alternans in an intact porcine model.
Alves Bento, Afonso S; Bacic, Danilo; Saran Carneiro, Juliana; Nearing, Bruce D; Fuller, Henrique; Justo, Fernanda A; Rajamani, Sridharan; Belardinelli, Luiz; Verrier, Richard L.
Affiliation
  • Alves Bento AS; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Bacic D; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Saran Carneiro J; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Nearing BD; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
  • Fuller H; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Justo FA; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Rajamani S; Gilead Sciences, Inc, Foster City and Fremont, California.
  • Belardinelli L; Gilead Sciences, Inc, Foster City and Fremont, California.
  • Verrier RL; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts. Electronic address: rverrier@bidmc.harvard.edu.
Heart Rhythm ; 12(12): 2508-14, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26190314
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Triazoles / Tachycardia, Ventricular Type of study: Etiology_studies Limits: Animals Language: En Journal: Heart Rhythm Year: 2015 Document type: Article Affiliation country: Brazil Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Triazoles / Tachycardia, Ventricular Type of study: Etiology_studies Limits: Animals Language: En Journal: Heart Rhythm Year: 2015 Document type: Article Affiliation country: Brazil Country of publication: United States