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Imidase catalyzing desymmetric imide hydrolysis forming optically active 3-substituted glutaric acid monoamides for the synthesis of gamma-aminobutyric acid (GABA) analogs.
Nojiri, Masutoshi; Hibi, Makoto; Shizawa, Hiroaki; Horinouchi, Nobuyuki; Yasohara, Yoshihiko; Takahashi, Satomi; Ogawa, Jun.
Affiliation
  • Nojiri M; Biotechnology Development Laboratories, Kaneka Corporation, 1-8 Miyamae, Takasago, Hyogo, 676-8688, Japan.
  • Hibi M; Industrial Microbiology, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
  • Shizawa H; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
  • Horinouchi N; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
  • Yasohara Y; Biotechnology Development Laboratories, Kaneka Corporation, 1-8 Miyamae, Takasago, Hyogo, 676-8688, Japan.
  • Takahashi S; Industrial Microbiology, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
  • Ogawa J; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan. ogawa@kais.kyoto-u.ac.jp.
Appl Microbiol Biotechnol ; 99(23): 9961-9, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26205522
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Alcaligenes faecalis / Burkholderiaceae / Amidohydrolases / Glutarates / Imides Language: En Journal: Appl Microbiol Biotechnol Year: 2015 Document type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Alcaligenes faecalis / Burkholderiaceae / Amidohydrolases / Glutarates / Imides Language: En Journal: Appl Microbiol Biotechnol Year: 2015 Document type: Article Affiliation country: Japan