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Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.
Siegert, Isabel; Schödel, Johannes; Nairz, Manfred; Schatz, Valentin; Dettmer, Katja; Dick, Christopher; Kalucka, Joanna; Franke, Kristin; Ehrenschwender, Martin; Schley, Gunnar; Beneke, Angelika; Sutter, Jörg; Moll, Matthias; Hellerbrand, Claus; Wielockx, Ben; Katschinski, Dörthe M; Lang, Roland; Galy, Bruno; Hentze, Matthias W; Koivunen, Peppi; Oefner, Peter J; Bogdan, Christian; Weiss, Günter; Willam, Carsten; Jantsch, Jonathan.
Affiliation
  • Siegert I; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany.
  • Schödel J; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU), 91054 Erlangen, Germany.
  • Nairz M; Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
  • Schatz V; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, 93053 Regensburg, Germany.
  • Dettmer K; Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.
  • Dick C; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, 93053 Regensburg, Germany.
  • Kalucka J; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU), 91054 Erlangen, Germany.
  • Franke K; Heisenberg Research Group, Department of Clinical Pathobiochemistry, Institute of Clinical Chemistry and Laboratory Medicine, University of Technology, 01307 Dresden, Germany.
  • Ehrenschwender M; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, 93053 Regensburg, Germany.
  • Schley G; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU), 91054 Erlangen, Germany.
  • Beneke A; Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Göttingen, 37073 Göttingen, Germany.
  • Sutter J; Department of Chemistry and Pharmacy, Inorganic Chemistry, Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91058 Erlangen, Germany.
  • Moll M; Department of Chemistry and Pharmacy, Inorganic Chemistry, Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91058 Erlangen, Germany.
  • Hellerbrand C; Department of Internal Medicine I, University of Regensburg, 93053 Regensburg, Germany.
  • Wielockx B; Heisenberg Research Group, Department of Clinical Pathobiochemistry, Institute of Clinical Chemistry and Laboratory Medicine, University of Technology, 01307 Dresden, Germany.
  • Katschinski DM; Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Göttingen, 37073 Göttingen, Germany.
  • Lang R; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany.
  • Galy B; Division of Virus-Associated Carcinogenesis, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Hentze MW; European Molecular Biology Laboratory, 69120 Heidelberg, Germany.
  • Koivunen P; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, 90014 Oulu, Finland.
  • Oefner PJ; Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.
  • Bogdan C; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany.
  • Weiss G; Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
  • Willam C; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU), 91054 Erlangen, Germany.
  • Jantsch J; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regen
Cell Rep ; 13(10): 2048-55, 2015 Dec 15.
Article in En | MEDLINE | ID: mdl-26628374
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypoxia-Inducible Factor 1, alpha Subunit / Ferritins / Prolyl Hydroxylases / Inflammation / Iron Limits: Animals Language: En Journal: Cell Rep Year: 2015 Document type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypoxia-Inducible Factor 1, alpha Subunit / Ferritins / Prolyl Hydroxylases / Inflammation / Iron Limits: Animals Language: En Journal: Cell Rep Year: 2015 Document type: Article Affiliation country: Germany