Enhancing adoptive T cell immunotherapy with microRNA therapeutics.

Ji, Yun; Hocker, James D; Gattinoni, Luca

Ji, Yun; Hocker, James D; Gattinoni, Luca.

Affiliation

Ji Y; Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD, USA. Electronic address: jiyun@mail.nih.gov.
Hocker JD; Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD, USA.
Gattinoni L; Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD, USA. Electronic address: gattinol@mail.nih.gov.

Semin Immunol ; 28(1): 45-53, 2016 02.

Article in En | MEDLINE | ID: mdl-26710685

Subject(s)

Cancer Vaccines/immunology; Immunotherapy, Adoptive/methods; MicroRNAs/genetics; Neoplasms/therapy; RNA, Small Untranslated/genetics; Receptors, Antigen, T-Cell/metabolism; T-Lymphocytes/physiology; Animals; Cell Differentiation/genetics; Cell Survival; Cytotoxicity, Immunologic; Humans; Immunity, Cellular/genetics; Lymphocyte Activation/genetics; MicroRNAs/immunology; Neoplasms/immunology; RNA, Small Untranslated/immunology; Receptors, Antigen, T-Cell/genetics; Signal Transduction; T-Lymphocytes/transplantation

Key words

Adoptive cell transfer; CD8(+) T cells; Microrna (miRNA); T cell differentiation; Tumor immunotherapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / T-Lymphocytes / Immunotherapy, Adoptive / Cancer Vaccines / MicroRNAs / RNA, Small Untranslated / Neoplasms Limits: Animals / Humans Language: En Journal: Semin Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2016 Document type: Article Country of publication: United kingdom

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