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Development and validation of a UPLC-MS/MS method for the novel folate-targeted small molecule drug conjugate EC1456 and its metabolites in tumor homogenates from mice.
Rao, Satish I; Pugh, Michael; Nelson, Melissa; Reddy, Joseph A; Klein, Patrick J; Leamon, Christopher P.
Affiliation
  • Rao SI; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN 47906, USA. Electronic address: srao749@gmail.com.
  • Pugh M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN 47906, USA.
  • Nelson M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN 47906, USA.
  • Reddy JA; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN 47906, USA.
  • Klein PJ; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN 47906, USA.
  • Leamon CP; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN 47906, USA.
J Pharm Biomed Anal ; 122: 148-56, 2016 Apr 15.
Article in En | MEDLINE | ID: mdl-26855286
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Chromatography, High Pressure Liquid / Tandem Mass Spectrometry / Small Molecule Libraries / Folic Acid / Neoplasms Limits: Animals Language: En Journal: J Pharm Biomed Anal Year: 2016 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Chromatography, High Pressure Liquid / Tandem Mass Spectrometry / Small Molecule Libraries / Folic Acid / Neoplasms Limits: Animals Language: En Journal: J Pharm Biomed Anal Year: 2016 Document type: Article Country of publication: United kingdom