Protective Effect of Tempol on Acute Kidney Injury Through PI3K/Akt/Nrf2 Signaling Pathway.

Zhang, Gensheng; Wang, Qiaoling; Zhou, Qin; Wang, Renjun; Xu, Minze; Wang, Huiping; Wang, Lei; Wilcox, Christopher S; Liu, Ruisheng; Lai, En Yin

Zhang, Gensheng; Wang, Qiaoling; Zhou, Qin; Wang, Renjun; Xu, Minze; Wang, Huiping; Wang, Lei; Wilcox, Christopher S; Liu, Ruisheng; Lai, En Yin.

Affiliation

Zhang G; Department of Physiology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Kidney Blood Press Res ; 41(2): 129-38, 2016.

Article in En | MEDLINE | ID: mdl-26894882

Subject(s)

Acute Kidney Injury/metabolism; Acute Kidney Injury/prevention & control; Antioxidants/therapeutic use; Cyclic N-Oxides/therapeutic use; NF-E2-Related Factor 2/biosynthesis; Phosphatidylinositol 3-Kinase/biosynthesis; Proto-Oncogene Proteins c-akt/biosynthesis; Animals; Antioxidants/pharmacology; Cyclic N-Oxides/pharmacology; Dose-Response Relationship, Drug; Lipid Peroxidation/drug effects; Lipid Peroxidation/physiology; Male; Mice; Mice, Inbred C57BL; Oxidative Stress/drug effects; Oxidative Stress/physiology; Signal Transduction/drug effects; Signal Transduction/physiology; Spin Labels; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic N-Oxides / Proto-Oncogene Proteins c-akt / NF-E2-Related Factor 2 / Acute Kidney Injury / Phosphatidylinositol 3-Kinase / Antioxidants Type of study: Prognostic_studies Limits: Animals Language: En Journal: Kidney Blood Press Res Journal subject: NEFROLOGIA Year: 2016 Document type: Article Affiliation country: China

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