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Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.
Lochhead, Pamela A; Clark, Jonathan; Wang, Lan-Zhen; Gilmour, Lesley; Squires, Matthew; Gilley, Rebecca; Foxton, Caroline; Newell, David R; Wedge, Stephen R; Cook, Simon J.
Affiliation
  • Lochhead PA; a Signalling Laboratory; The Babraham Institute ; Cambridge , UK.
  • Clark J; b Biological Chemistry Facility; The Babraham Institute ; Cambridge , UK.
  • Wang LZ; c The Northern Institute for Cancer Research; University of Newcastle upon Tyne , Newcastle , UK.
  • Gilmour L; d Cancer Research Technology; The Beatson Institute for Cancer Research; Garscube Estate ; Glasgow , UK.
  • Squires M; e Current address: Translational Radiation Biology; The Beatson Institute for Cancer Research; Garscube Estate ; Glasgow , UK.
  • Gilley R; a Signalling Laboratory; The Babraham Institute ; Cambridge , UK.
  • Foxton C; f Current address: Novartis ; Basel , Switzerland.
  • Newell DR; a Signalling Laboratory; The Babraham Institute ; Cambridge , UK.
  • Wedge SR; g Cancer Research Technology; CRT Discovery Laboratories; London Bioscience Innovation Centre ; London , UK.
  • Cook SJ; h Current address: Centre for Drug Development ; Cancer Research UK ; London , UK.
Cell Cycle ; 15(4): 506-18, 2016.
Article in En | MEDLINE | ID: mdl-26959608
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Proto-Oncogene Proteins p21(ras) / Proto-Oncogene Proteins B-raf / Mitogen-Activated Protein Kinase 7 Limits: Humans Language: En Journal: Cell Cycle Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Proto-Oncogene Proteins p21(ras) / Proto-Oncogene Proteins B-raf / Mitogen-Activated Protein Kinase 7 Limits: Humans Language: En Journal: Cell Cycle Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United States