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Triamcinolone Acetonide and Bevacizumab Induced Raised Intraocular Pressure in An Elderly Male Diabetic Patient - A Case Report.
Golakiya, Hiral N; Hirapara, Hiren N; Parmar, Sugnesh J; Naik, Viren N; Tripathi, Chandrabhanu B.
Affiliation
  • Tripathi CB; Department of Pharmacology, Government Medical College, Bhavnagar 364001 (Gujarat), India.
Curr Drug Saf ; 11(3): 270-1, 2016.
Article in En | MEDLINE | ID: mdl-27048193
Intravitreal triamcinolone and bevacizumab are emerging treatment modalities for the patients of macular oedema; however, they are known to raise intraocular pressure. A 61 year old diabetic male patient developed glaucoma after administration of triamcinolone acetonide and bevacizumab intravitreally for treatment of macular oedema. His intraocular pressure was raised up to about 42 mm Hg. Such high and sustained rise in intraocular pressure may lead to vision loss by damaging the optic nerve. The patient was managed by local as well as systematic therapy and was recovered after 1 month from the occurrence of an event. Intraocular pressure should be monitored in patients receiving intravitreal triamcinolone and bevacizumab. Risk benefit analysis must be done before using IVTA and IVB in patients with diabetic macular oedema.
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Collection: 01-internacional Database: MEDLINE Main subject: Triamcinolone Acetonide / Diabetes Mellitus / Bevacizumab / Intraocular Pressure Type of study: Diagnostic_studies Limits: Humans / Male / Middle aged Language: En Journal: Curr Drug Saf Year: 2016 Document type: Article Country of publication: United Arab Emirates
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Collection: 01-internacional Database: MEDLINE Main subject: Triamcinolone Acetonide / Diabetes Mellitus / Bevacizumab / Intraocular Pressure Type of study: Diagnostic_studies Limits: Humans / Male / Middle aged Language: En Journal: Curr Drug Saf Year: 2016 Document type: Article Country of publication: United Arab Emirates