Platycodin D exerts anti-tumor efficacy in H22 tumor-bearing mice via improving immune function and inducing apoptosis.

Li, Wei; Tian, Yu-Hong; Liu, Ying; Wang, Zi; Tang, Shan; Zhang, Jing; Wang, Ying-Ping

Li, Wei; Tian, Yu-Hong; Liu, Ying; Wang, Zi; Tang, Shan; Zhang, Jing; Wang, Ying-Ping.

Affiliation

Li W; College of Chinese Medicinal Materials, Jilin Agricultural University, China.

J Toxicol Sci ; 41(3): 417-28, 2016.

Article in En | MEDLINE | ID: mdl-27193733

Subject(s)

Angiogenesis Inhibitors/pharmacology; Apoptosis/drug effects; Carcinoma, Hepatocellular/drug therapy; Immunologic Factors/pharmacology; Liver Neoplasms/drug therapy; Saponins/pharmacology; Triterpenes/pharmacology; Animals; Carcinoma, Hepatocellular/immunology; Carcinoma, Hepatocellular/metabolism; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Cytokines/blood; Dose-Response Relationship, Drug; Liver Neoplasms/immunology; Liver Neoplasms/metabolism; Liver Neoplasms/pathology; Male; Mice, Inbred ICR; Proto-Oncogene Proteins c-bcl-2/metabolism; Signal Transduction/drug effects; Time Factors; Tumor Burden/drug effects; Vascular Endothelial Growth Factor A/blood; bcl-2-Associated X Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saponins / Triterpenes / Apoptosis / Carcinoma, Hepatocellular / Angiogenesis Inhibitors / Immunologic Factors / Liver Neoplasms Limits: Animals Language: En Journal: J Toxicol Sci Year: 2016 Document type: Article Affiliation country: China Country of publication: Japan

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