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Cellular heterogeneity mediates inherent sensitivity-specificity tradeoff in cancer targeting by synthetic circuits.
Morel, Mathieu; Shtrahman, Roman; Rotter, Varda; Nissim, Lior; Bar-Ziv, Roy H.
Affiliation
  • Morel M; Department of Materials and Interfaces, Weizmann Institute of Science, Rehovot, Israel, 76100; Ecole Normale Supérieure, Paris Sciences et Lettres (PSL) Research University, Université Pierre et Marie Curie, CNRS, Département de Chimie, UMR 8640 PASTEUR, 75005 Paris, France; Université Pierre et Mar
  • Shtrahman R; Department of Materials and Interfaces, Weizmann Institute of Science, Rehovot, Israel, 76100;
  • Rotter V; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, 76100;
  • Nissim L; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02139 liorni@mit.edu roy.bar-ziv@weizmann.ac.il.
  • Bar-Ziv RH; Department of Materials and Interfaces, Weizmann Institute of Science, Rehovot, Israel, 76100; liorni@mit.edu roy.bar-ziv@weizmann.ac.il.
Proc Natl Acad Sci U S A ; 113(29): 8133-8, 2016 07 19.
Article in En | MEDLINE | ID: mdl-27385823
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Regulatory Networks / Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Regulatory Networks / Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Document type: Article Country of publication: United States