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Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development.
Zhao, Lijuan; Frock, Richard L; Du, Zhou; Hu, Jiazhi; Chen, Liang; Krangel, Michael S; Alt, Frederick W.
Affiliation
  • Zhao L; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine Children's Hospital Boston, Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Frock RL; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine Children's Hospital Boston, Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Du Z; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine Children's Hospital Boston, Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Hu J; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine Children's Hospital Boston, Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Chen L; Department of Immunology, Duke University Medical Center, Durham, NC 27710.
  • Krangel MS; Department of Immunology, Duke University Medical Center, Durham, NC 27710 michael.krangel@duke.edu alt@enders.tch.harvard.edu.
  • Alt FW; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine Children's Hospital Boston, Department of Genetics, Harvard Medical School, Boston, MA 02115 michael.krangel@duke.edu alt@enders.tch.harvard.edu.
J Exp Med ; 213(9): 1921-36, 2016 08 22.
Article in En | MEDLINE | ID: mdl-27526713
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Receptors, Antigen, T-Cell, gamma-delta / Homeodomain Proteins / V(D)J Recombination Limits: Animals Language: En Journal: J Exp Med Year: 2016 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Receptors, Antigen, T-Cell, gamma-delta / Homeodomain Proteins / V(D)J Recombination Limits: Animals Language: En Journal: J Exp Med Year: 2016 Document type: Article Country of publication: United States