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Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones).
Jantsch, Andrea; Nieto, Lidia; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth; Jiménez-Barbero, Jesús; Díaz, J Fernando; Canales, Ángeles; Altmann, Karl-Heinz.
Affiliation
  • Jantsch A; Department of Chemistry and Applied Biosciences, Insitute of Pharmaceutical Sciences, ETH Zürich, CH-8093 Zürich, Switzerland. a.jantsch@hotmail.com.
  • Nieto L; Department of Organic Chemistry I, Fac. C. C. Químicas, Universidad Complutense de Madrid, ES-28040 Madrid, Spain. linietog@gmail.com.
  • Gertsch J; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. linietog@gmail.com.
  • Rodríguez-Salarichs J; Institute of Biochemistry and Molecular Medicine, University of Bern, CH-3012 Bern, Switzerland. juerg.gertsch@ibmm.unibe.ch.
  • Matesanz R; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. javierr@cib.csic.es.
  • Jiménez-Barbero J; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. ruth.m.r@cib.csic.es.
  • Díaz JF; CIC bioGUNE, 48170 Derio, Spain. jjbarbero@cicbiogune.es.
  • Canales Á; Ikerbasque, Basque Foundation for Science, 48009 Bilbao, Spain. jjbarbero@cicbiogune.es.
  • Altmann KH; Department of Organic Chemistry II, Faculty of Science & Technology, University of the Basque Country, 48940 Leioa, Bizkaia, Spain. jjbarbero@cicbiogune.es.
Molecules ; 21(8)2016 Aug 03.
Article in En | MEDLINE | ID: mdl-27527129
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tubulin / Epothilones / Antineoplastic Agents Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2016 Document type: Article Affiliation country: Switzerland Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tubulin / Epothilones / Antineoplastic Agents Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2016 Document type: Article Affiliation country: Switzerland Country of publication: Switzerland