Mutations of myelodysplastic syndromes (MDS): An update.

Ganguly, Bani Bandana; Kadam, N N

Ganguly, Bani Bandana; Kadam, N N.

Affiliation

Ganguly BB; MGM Center for Genetic Research & Diagnosis, MGM New Bombay Hospital, New Mumbai, India. Electronic address: mgmgeneticlab@yahoo.com.
Kadam NN; MGM Medical College and Hospital, Navi Mumbai, India.

Mutat Res Rev Mutat Res ; 769: 47-62, 2016.

Article in En | MEDLINE | ID: mdl-27543316

Subject(s)

Genetic Association Studies; Genetic Predisposition to Disease; Mutation; Myelodysplastic Syndromes/genetics; Animals; Biomarkers; Cell Transformation, Neoplastic/genetics; Cell Transformation, Neoplastic/metabolism; Chromosome Aberrations; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation/drug effects; Humans; Molecular Targeted Therapy; Monosomy; Myelodysplastic Syndromes/drug therapy; Myelodysplastic Syndromes/metabolism; Myelodysplastic Syndromes/mortality; Prognosis; Signal Transduction/drug effects

Key words

Complex chromosomal aberration; EZH2/IDH inhibitors as drug targets; Monosomal karyotype; Mutations in pathway genes; Myelodysplastic syndromes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myelodysplastic Syndromes / Genetic Predisposition to Disease / Genetic Association Studies / Mutation Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Mutat Res Rev Mutat Res Year: 2016 Document type: Article

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