Effect of H4R antagonist N-(2-aminoethyl)-5-chloro-1H-indol-2-carboxamides and 5-chloro-2-(piperazin-1-ylmethyl)-1H-benzimidazole on histamine and 4-methylhistamine-induced mast cell response.

Nagarajan, Gomathi; Mariappanadar, Vairamani; Tamizh, Muthu; Kaliappan, Ilango; Elden, Berla Thangam

Nagarajan, Gomathi; Mariappanadar, Vairamani; Tamizh, Muthu; Kaliappan, Ilango; Elden, Berla Thangam.

Affiliation

Nagarajan G; a Department of Biotechnology , School of Bioengineering, SRM University , Kattankulathur , Tamil Nadu , India.
Mariappanadar V; a Department of Biotechnology , School of Bioengineering, SRM University , Kattankulathur , Tamil Nadu , India.
Tamizh M; b Interdisciplinary Institute of Indian System of Medicine (IIISM), SRM University , Kattankulathur , Tamil Nadu , India.
Kaliappan I; c Department of Pharmaceutical Chemistry , SRM College of Pharmacy, SRM University , Kattankulathur , Tamil Nadu , India.
Elden BT; a Department of Biotechnology , School of Bioengineering, SRM University , Kattankulathur , Tamil Nadu , India.

J Recept Signal Transduct Res ; 37(3): 304-313, 2017 Jun.

Article in En | MEDLINE | ID: mdl-27807993

Subject(s)

Histamine Antagonists/administration & dosage; Hypersensitivity/drug therapy; Inflammation/drug therapy; Receptors, G-Protein-Coupled/antagonists & inhibitors; Receptors, Histamine/metabolism; Calcium/metabolism; Histamine/metabolism; Histamine Antagonists/chemistry; Humans; Hypersensitivity/metabolism; Inflammation/metabolism; Inflammation/pathology; Mast Cells/drug effects; Methylhistamines/administration & dosage; Methylhistamines/chemistry; NF-kappa B/biosynthesis; Phosphorylation; Receptors, Histamine H4; Signal Transduction

Key words

4-methylhistamine; Compound A; Compound L; H4R antagonist; histamine; mast cells

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Histamine / Receptors, G-Protein-Coupled / Histamine Antagonists / Hypersensitivity / Inflammation Limits: Humans Language: En Journal: J Recept Signal Transduct Res Journal subject: BIOQUIMICA / FISIOLOGIA Year: 2017 Document type: Article Affiliation country: India Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google